The first children participate in European research carried out by UMC Utrecht: does a corona vaccination also work?

Editorial Medicalfacts/ Janine Budding 30 August 2022 – 07:36

Protect children aged 5 to 11 against corona? UMC Utrecht is investigating whether one shot of the Pfizer-BioNTech vaccine protects as well as two shots in children who have had corona. Children who wish to be vaccinated can enroll in this study. Elsa, seven, is the first child to recently participate in this CoVacc study.

Elsa, a fictitious name for privacy, is a seven-year-old girl who herself wanted to participate in the study. So her mother gave her up. “She wanted to participate, is fascinated by hospital series and is always eager to help other children. It’s an already approved vaccine, so I didn’t see any problems.’

Why this research in children at this young age? Dr. Patricia Bruijning, paediatrician, epidemiologist and principal researcher of the CoVacc study: “When children are vaccinated against corona, they get two injections as standard. But if you’ve had corona before, sometimes you only get one shot. We want to investigate – for children , who want to be vaccinated – whether one shot works as well as two. But with possibly fewer side effects and less stress.”

The CoVacc study is looking for 200 children aged 5 to 11 in Europe, including the Netherlands, to investigate what is actually best: one or two injections.

Register children

Children who are at least 5 and at most 11 years old can participate in the CoVacc study. Parents or guardians can register them. It is possible to participate if the child has already had corona and has not yet received a vaccination against corona, but would like to.

You can register for this study via By registering, no obligation is entered into.

Approved corona vaccine

The study uses the pediatric vaccine from Pfizer-BioNTech, which is approved by the EMA (European Medicine Agency). Bruijning: “The standard vaccination schedule for children aged 5 and over prescribes that two injections of 10 micrograms are given. In some countries, however, only 1 shot is given if children have had corona before and you do not belong to a risk group. An injection causes half the stress for the child and the parents and is expected to cause fewer side effects, but does it work just as well? To investigate this, half of the children receive one injection, and the other half two injections. In addition, we want to know how long one or two injections provide protection for young children and whether it provides protection against new variants of SARS-CoV-2.”

CoVacc is part of the European VACCELERATE project “A Pan-European Vaccine Development Network”, which creates a network ready to tackle new pandemics and increase vaccine development capacity in Europe. VACCELERATE has received support from the European Union’s Horizon 2020 Research and Innovation Program under grant agreement no. 101037867.

Editorial Medicalfacts/ Janine Budding

I specialize in interactive news for health care providers, so that health care providers are informed every day of the news that may be relevant to them. Both lay news and news specific to healthcare providers and prescribers. Social media, Women’s Health, Patient advocacy, patient empowerment, personalized medicine & Care 2.0 and the social domain are spearheads for me to pay extra attention to.

I studied physiotherapy and health economics. In addition, I am a registered independent client supporter and informal care broker. I have extensive experience in various positions within the healthcare, social domain and the medical, pharmaceutical industry, nationally and internationally. And has broad medical knowledge of most specialties within the healthcare system. And of the health laws, from which the health service is regulated and financed. Every year I attend most of the leading medical conferences in Europe and America to keep my knowledge up to date and to keep up with the latest developments and innovations. I am currently working on a master’s in applied psychology.

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